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Introductory Organic Chemistry - Lecture 34

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Lecture 34 - Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes

Guest Lecture on Stereospecific Catalysis by Barry Sharpless; Molecular Mechanics of cyclobutane and cyclopentane puckering

Professor Barry Sharpless of Scripps describes the Nobel-prizewinning development of titanium-based catalysts for stereoselective oxidation, the mechanism of their reactions, and their use in preparing esomeprazole. Conformational energy of cyclic alkanes illustrates the use of molecular mechanics.

Prof. J. Michael McBride
CHEM 125: Freshman Organic Chemistry, Fall 2008
(Yale University: Open Yale)
http://oyc.yale.edu
Date accessed: 2009-11-11
License: Creative Commons BY-NC-SA

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